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Table 6 Univariable and multivariable logistic regression analysis for predictive factors of severe LGIB

From: A clinical predictive model for risk stratification of patients with severe acute lower gastrointestinal bleeding

Variable

Univariate analysis

Multivariable analysis

Odds ratio (95% CI)

P value

Odds ratio (95% CI)

P value

Age

  

 

  > 60

1.13 (0.79–1.63)

0.5

  

Gender, male

1.03 (0.75–1.43)

0.84

 

CCM > 2

1.38 (0.97–1.95)

0.075

  

CKD

1.96 (1.18–3.26)

0.01

 

Antiplatelet/anticoagulant

1.50 (1.07–2.11)

0.02

1.93 (1.26–2.94)

0.002

Active PRB

1.80 (1.29–2.51)

0.001

2.36 (1.55–3.59)

 < 0.001

HR1 ≥ 100

2.79 (1.78–4.38)

 < 0.001

3.74 (2.17–6.46)

 < 0.001

SBP < 90

13.91 (3.13–61.73)

0.001

15.46 (3.12–76.73)

 < 0.001

MAP < 65

7.26 (2.01–26.32)

0.003

 

Hb < 9

16.87 (10.12–28.11)

 < 0.001

20.74 (11.89–36.17)

 < 0.001

Hct < 35%

9.40 (6.40–13.83)

 < 0.001

 

AKI/AOCKD

2.22 (1.58–3.12)

 < 0.001

 

INR ≥ 1.5

1.97 (0.91–4.28)

0.085

 

HCO3 ≤ 19

3.77 (2.00–7.10)

 < 0.001

3.69 (1.65–8.22)

0.001

  1. CCM Charlson Comorbidity Index, CKD chronic kidney disease, PRB PR bleeding, HR heart rate, SBP systolic blood pressure, MAP mean arterial pressure, Hb haemoglobin, Hct Hematocrit, AKI acute kidney injury, AOCKD acute on chronic kidney disease, INR international normalised ratio, HCO3 bicarbonate (acidosis)