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Table 6 Univariable and multivariable logistic regression analysis for predictive factors of severe LGIB

From: A clinical predictive model for risk stratification of patients with severe acute lower gastrointestinal bleeding

Variable Univariate analysis Multivariable analysis
Odds ratio (95% CI) P value Odds ratio (95% CI) P value
Age    
  > 60 1.13 (0.79–1.63) 0.5   
Gender, male 1.03 (0.75–1.43) 0.84  
CCM > 2 1.38 (0.97–1.95) 0.075   
CKD 1.96 (1.18–3.26) 0.01  
Antiplatelet/anticoagulant 1.50 (1.07–2.11) 0.02 1.93 (1.26–2.94) 0.002
Active PRB 1.80 (1.29–2.51) 0.001 2.36 (1.55–3.59)  < 0.001
HR1 ≥ 100 2.79 (1.78–4.38)  < 0.001 3.74 (2.17–6.46)  < 0.001
SBP < 90 13.91 (3.13–61.73) 0.001 15.46 (3.12–76.73)  < 0.001
MAP < 65 7.26 (2.01–26.32) 0.003  
Hb < 9 16.87 (10.12–28.11)  < 0.001 20.74 (11.89–36.17)  < 0.001
Hct < 35% 9.40 (6.40–13.83)  < 0.001  
AKI/AOCKD 2.22 (1.58–3.12)  < 0.001  
INR ≥ 1.5 1.97 (0.91–4.28) 0.085  
HCO3 ≤ 19 3.77 (2.00–7.10)  < 0.001 3.69 (1.65–8.22) 0.001
  1. CCM Charlson Comorbidity Index, CKD chronic kidney disease, PRB PR bleeding, HR heart rate, SBP systolic blood pressure, MAP mean arterial pressure, Hb haemoglobin, Hct Hematocrit, AKI acute kidney injury, AOCKD acute on chronic kidney disease, INR international normalised ratio, HCO3 bicarbonate (acidosis)