Table 2 Data from comparative studies included in the meta-analysis
Chang 2022 | Tabchouri 2019 | Vinet 2006 | ||||
|---|---|---|---|---|---|---|
TIPS (n = 45) | Control (n = 45) | TIPS (n = 66) | Control (n = 68) | TIPS (n = 18) | Control (n = 17) | |
Age | 63 (43–80) | 64 (40–77) | 60.9 (38–81) | 65.8 (42–80) | 58 (14) | 62 (12) |
Sex (female), n (%) | 13 (29%) | 13 (29%) | 16 (24%) | 14 (20%) | 4 (22%) | 6 (35%) |
Cirrhosis etiology | Alcohol: 32 (71%), Viral hep: 4 (9%), other: 9 (20%) | Alcohol: 32 (71%), Viral hep (9%): 4, other: 9 (20%) | Alcohol: 53 (80.3%), Hep C: 6 (6.8%), NASH: 4 (6%), other: 3 (3.4%) | Alcohol: 50 (73.5%), Hep C: 7 (10.2%), NASH: 3 (4.4%), other: 8 (11.8%) | Alcohol: 7 (39%) | 6 (35%) |
MELD score | 11 (6–17) | 10 (6–18) | 11 (6–21) | 11 (6–25) | NR | NR |
Child–Pugh class | A: 10, B: 35 | A: 10, B: 35 | A: 40 (60%), B: 24 (37%), C: 2 (3%) | A: 47 (69%), B: 21 (31%), C: 0 | Pugh score: 7.7 (6–10) | Pugh score: 6.2 (5–9) |
Surgical procedures | Non-visceral: 21 (47%), Visceral: 24 (5,%) | Non-visceral: 21 (47%), Visceral: 24 (5,%) | Colorectal: 24 (51.5%), upper GI and pancreatic: 12 (18.2%), Hernia and incisional hernia: 9 (13.6%), cholecystectomy: 5 (7.6%), other: 6 (9.1%) | Colorectal: 38 (57,4%), upper GI and pancreatic: 4 (5,9%), Hernia and incisional hernia: 9 (13.2%), cholecystectomy: 10 (14,7%), other: 7 (10,2%) | Colectomy: 10, duodenopancreatectomy: 1, gastrectomy: 5, nephrectomy: 1. small bowel resection: 1 | Colectomy: 13, duodenopancreatectomy: 2, gastrectomy: 1, nephrectomy: 1, small bowel resection: 0 |
Emergency surgery, n (%) | 7 (16%) | 7 (16%) | NR | NR | NR | NR |
Control group selection method | 1:1 Propensity score matched groups | Inverse probability weighting—propensity score | Not matching. Retrospective cohort study including all patients who underwent TIPS placement before an elective abdominal operation and compared to all cirrhotic patients who underwent elective abdominal surgeries without TIPS between 1992 and 2002 | |||
Postop Outcomes | Data for matched groups (TIPS: 45 vs Controls: 45) | Data for matched groups (TIPS: 56 vs controls: 68) | Data for all the cohort (TIPS: 18 vs. Controls: 17) | |||
Ascites | 15 (33%) | 25 (56%) | 11 (20.4%) | 26 (38.2%) | NR | NR |
HE | 5 (11%) | 4 (9%) | NR | NR | 4 (22%) | 5 (29%) |
Perioperative blood transfusions | 11 (24%) | 20 (44%) | 17 (30.4%) | 9 (13.2%) | 6 (33%) | 7 (41%) |
ACLF | 4 (8.9%) | 13 (28.9%) | 8 (14.5%) | 2 (2.9%) | 3 (16%) | 3 (18%) |
90-day mortality | 5 (11.1%) | 11 (24%) | 4 (7.5%) | 5 (7.8%) | 6 (33%) | 4 (23%) |