Fig. 3

Multiple linear regression analyses to estimate adjusted effects of restrictive RBC transfusion strategy on ICU-free, ventilator-free, and catecholamine-free days, according to the initial lactate levels, setting liberal strategy as a reference. Analyses were conducted for each lactate level category and were adjusted for factors including age, sex, systolic blood pressure on ED arrival, the presence of a severe head injury (defined as an Abbreviated Injury Scale of 4 or 5 for the head), injury severity score, initial hemoglobin levels, and the need for major hemostatic interventions. Interactions between transfusion strategy and initial lactate levels were tested. RBC red blood cells, ICU intensive care unit, ED emergency department, CI confidence interval