Table 2 Comparison of the outcomes between restrictive and liberal strategy group based on initial lactate levels

28-day survival, n (%)

65 (97)

60 (94)

0.37

62 (95)

44 (92)

0.42

60 (85)

72 (89)

0.43

Length of ICU stay, median (IQR), days

4 (3–8)

6 (3–15)

0.05

6 (3–14)

6 (3–15)

0.60

9 (3–17)

6 (3–12)

0.55

Event-free days during the first 28 days, median (IQR)

ICU-free days

23 (18–24)

21 (9–24)

0.06

18 (12–24)

19 (9–23)

0.27

15 (2–21)

17 (3–24)

0.29

Ventilator-free days

28 (26–28)

26 (20–28)

0.003

25 (20–28)

23 (16–28)

0.42

21 (5–26)

23 (17–26)

0.38

Catecholamine-free days

28 (28–28)

28 (28–28)

0.74

28 (28–28)

28 (26–28)

0.77

28 (24–28)

28 (26–28)

0.2

Organ failure during the first 7 days, n (%)

5 (7)

4 (6)

0.78

10 (15)

3 (6)

0.13

12 (17)

15 (19)

0.30

Renal failure

2 (3)

1 (2)

0.59

3 (5)

1 (2)

0.47

2 (3)

8 (10)

0.08

Respiratory failure

4 (6)

4 (6)

0.95

9 (14)

3 (6)

0.2

10 (14)

10 (12)

0.8

Liver failure

0

0

N/A

1 (2)

1 (2)

0.83

1 (1)

2 (2)

0.64

Any complications during the first 28 days, n (%)

11 (16)

7 (11)

0.36

12 (18)

9 (19)

0.97

13 (18)

15 (19)

0.97

Deep venous thrombosis

9 (13)

5 (8)

0.30

9 (14)

6 (13)

0.84

6 (8)

5 (6)

0.59

Pulmonary embolism

1 (1)

0

0.33

0 (0)

2 (4)

0.1

4 (6)

0

0.03

Cerebral infarction

1 (1)

0

0.33

2 (3)

0

0.22

2 (3)

2 (2)

0.89

Acute myocardial infarction

0

0

N/A

0

0

N/A

0

0

N/A

Bowel ischemia

0

0

N/A

0

0

N/A

1 (1)

1 (1)

0.93

Transfusion-related acute lung injury

0

0

N/A

0

0

N/A

0

0

N/A

Sepsis

1 (1)

2 (3)

0.53

1 (2)

2 (4)

0.39

3 (4)

8 (10)

0.18