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Knowledge, awareness, and attitude towards infection prevention and management among surgeons: identifying the surgeon champion

World Journal of Emergency Surgery volume 13, Article number: 37 (2018) Cite this article

Abstract

Despite evidence supporting the effectiveness of best practices of infection prevention and management, many surgeons worldwide fail to implement them. Evidence-based practices tend to be underused in routine practice. Surgeons with knowledge in surgical infections should provide feedback to prescribers and integrate best practices among surgeons and implement changes within their team. Identifying a local opinion leader to serve as a champion within the surgical department may be important. The “surgeon champion” can integrate best clinical practices of infection prevention and management, drive behavior change in their colleagues, and interact with both infection control teams in promoting antimicrobial stewardship.

Background

In 2017, a global declaration for appropriate use of antimicrobials across the surgical pathway was shared by over 230 experts from 83 different countries [1]. Within this declaration, the authors highlighted the effects of antibiotic exposure, misuse, and overuse on antibiotic resistance and outlined the fundamental principles of appropriate antibiotic prophylaxis and therapy in surgery.

In that declaration, efforts to prevent healthcare-associated infections (HAIs) were not specifically highlighted [2]. HAIs including surgical site infection, ventilator-associated pneumonia, central line-associated bloodstream infection, and catheter-associated urinary tract infection are the most common nosocomial infections. Healthcare-associated infections continue to be of significant importance in surgical patients.

Surgical site infections (SSIs) are a major clinical problem in terms of morbidity, mortality, length of hospital stay, and overall direct and indirect costs globally [3, 4]. However, knowledge, attitudes, and awareness of infection prevention and control measures vary significantly among surgeons. Most significantly, a gap seems to exist between best evidence and clinical practice with regard to SSIs prevention.

The World Health Organization (WHO) [5], the Centers for Disease Control and Prevention (CDC) [6], and a combined effort by the American College of Surgeons/Surgical Infection Society [7, 8] have recently published guidelines for the prevention of SSIs. Despite clear evidence and guidelines to direct SSIs prevention strategies, compliance is unacceptably poor [9].

Preoperative antibiotic prophylaxis (PAP) is a cornerstone of SSIs prevention. The use of PAP contributes considerably to the total amount of antibiotics used in hospitals worldwide. PAP has been shown to be an effective measure for the prevention of SSIs, but its use should be limited to specific, well-accepted indications to avoid cost, toxicity, and antimicrobial resistance, and should never substitute for the good medical practice of infection prevention and control. Guidelines stress the importance of cessation of antibiotic prophylaxis immediately after surgery and refrain from the extension of prophylaxis outside the operating theater [5]. High rates of inappropriate use of prophylactic antibiotics in surgery continue to be reported in the literature [9]. In Appendix 1, seven strategies for correct antibiotic prophylaxis are illustrated.

Antibiotic therapy is an additional key component of daily surgical practice. Antibiotics are life-saving when treating bacterial infections but are often used inappropriately, specifically when not indicated. Antibiotic therapy plays an integral role in the management of surgical infections, especially in critically ill patients who require immediate empiric antibiotic therapy. Poor antibiotic coverage and inappropriate regimens are the variables most strongly associated with unfavorable outcomes [10, 11]. The timing, regimen, dose, route of administration, and duration of antibiotic therapy should be always optimized. In most patients with surgical infections, antibiotic therapy aims to treat any residual infection after adequate source control. In these patients, prolonging antibiotic treatment, which can lead to antibiotic resistance, does not prevent the persistence or recurrence of the infection. When source control is obtained, the duration of antibiotic therapy should be shortened as much as possible, unless there are special circumstances that require prolonging antimicrobial therapy, such as signs of an ongoing infection. Patients who have systemic signs of sepsis beyond 5 to 7 days of treatment warrant diagnostic investigation to determine an ongoing uncontrolled source of infection needing intervention [8]. In Appendix 2, ten strategies for correct antibiotic therapy are illustrated.

The surgeon as a champion in preventing and treating infections

Surgeons prescribing antibiotics have two opposing responsibilities. They have to (1) offer optimal therapy for the individual patient under their care and (2) restrain from overprescribing antibiotics to preserve their efficacy and minimize the rate of emergence of antimicrobial resistance, while also preventing collateral damage from antibiotics (such as Clostridium difficile infections) [12].

Because most surgeons have already established their attitudes and behaviors with regard to antibiotic usage, it is difficult to change their deeply established views and practice patterns. A range of factors such as diagnostic uncertainty, fear of clinical failure, time pressure, or organizational issues can influence prescribing decisions. However, due to cognitive dissonance (recognizing that an action is necessary but not implementing it), it is very challenging to change the prescribing behavior [1].

Surgeons should be aware of their role and responsibility for maintaining the effectiveness of current and future antibiotics. Although most of them are aware of the problem of antimicrobial resistance (AMR), many still underestimate this problem in their own hospital and in their patients. Inappropriate use of antibiotics, as well as poor prevention and control of infections such as hand hygiene, is contributing to the development of AMR. Surgeons are at the forefront in managing patients with infections and should take a proactive role in ensuring both effective antibiotic therapy and the avoidance of inappropriate and unnecessary antibiotic exposure [12].

Successful and cost-effective strategies to reduce AMR should involve a multi-faceted approach aimed at optimizing antibiotic use, strengthening surveillance and infection prevention and control, and improving clinician education regarding the appropriate use of antibiotics.

A growing body of evidence demonstrates that hospital-based programs dedicated to improving antibiotic use can both optimize the treatment of infections and reduce the adverse events associated with antibiotic use [1]. “Antibiotic stewardship programs” (ASPs) may significantly reduce the incidence of antimicrobial resistance and Clostridium difficile infections in hospitalized patients [1]. Every hospital worldwide should utilize the existing resources to create effective ASPs with a multi-disciplinary team. However, the best strategies to establish an ASPs are not well defined.

ASPs should be linked to infection control and prevention programs in order to improve antibiotic prescribing practices and to prevent infections.

Dedicated efforts, such as the establishment of locally adopted multi-disciplinary, evidence-based protocols and guidelines; unit specific antibiotic sensitivity data; and compliance monitoring, are required to maximize the performance.

To investigate the effects of the antibiotic stewardship program on prevention and control of SSIs during clean surgery, Liu et al. [13] compared the effect before and after an antibiotic stewardship program intervention. From January 1, 2010, to December 31, 2016, 41,426 patients underwent clean surgeries in a grade III, class A hospital. The rate of prophylactic antibiotic use in the 41,426 clean surgeries was reduced from 82.9 to 28.0% after the interventions. The rate of antibiotic agents administered within 120 min of the first incision increased from 20.8 to 85.1%. The rate at which prophylactic antimicrobial agents were discontinued in the first 24 h after surgery increased from 22.1 to 60.4%. Appropriate antibiotic selection increased from 37.0 to 93.6%. Prophylactic antibiotic re-dosing increased from 3.8 to 64.8%. The SSI rate decreased from 0.7 to 0.5% (p < 0.05). The pathogen detection rate increased from 16.7 up to 41.8% after intervention. The intensity of antibiotic consumption reduced from 74.9 defined daily doses (DDDs) per 100 bed-days to 34.2 DDDs per 100 bed-days after the interventions.

Van Kasteren et al. [14] in a prospective multi-site study of elective procedures in 13 Dutch hospitals evaluated the quality of prophylaxis auditing before and after an intervention consisting of performance feedback and implementation of national clinical practice guidelines. Antimicrobial use decreased from 121 to 79 DDD/100 procedures, and costs reduced by 25% per procedure. After the intervention, the antibiotic choice was inappropriate in only 37.5% of the cases instead of in 93.5% expected cases prior to the intervention. Prolonged prophylaxis was observed in 31.4% instead of 46.8% expected cases and inappropriate timing in 39.4% instead of the expected 51.8%. Time series analysis showed that all improvements were statistically significant (p < 0.01). The overall SSI rates before and after intervention were 5.4% (95% CI 4.3–6.5) and 4.6% (95% CI 3.6–5.4), respectively.

Raising awareness is a crucial factor in changing behaviors. Efforts to improve educational programs are thus required, and this should preferably be complemented by active interventions such as prospective audits and feedback to clinicians to stimulate further changes. It would be advisable to introduce specific courses and training about antibiotics in the core curriculum of medical students, with emphasis on the rational prescription of antibiotics that emphasizes more the behavior of medical students towards antibiotics use rather than the advance of knowledge alone [15].

The best means of improving ASPs worldwide should involve collaboration among various specialties within a healthcare institution including prescribing clinicians. ASPs have many contributors, steps, and actions specifically related to the prevention and management of infection. The multidisciplinary approach reinforces the concept that all professionals bring with them their particular expertise and are responsible for their respective contributions. In this context, the direct involvement of surgeons can be highly effective.

Surgeons with adequate knowledge in surgical infection who are involved in an ASPs may provide feedback and integrate the best practices of infection prevention and treatment among surgeons.

Very few studies have focused on the relationship between ASPs and surgeons. In 2011, Dortch et al. [16] reported the results of a surgeon-led infection reduction and antibiotic stewardship program in two separate ICUs, one trauma and one surgical. Components of the program included unit-specific empiric and therapeutic antibiotic protocols for healthcare-acquired infections, prophylaxis guidelines, and numerous infection reduction strategies. They demonstrated a marked reduction in infectious complications, multidrug-resistant pathogens, and broad-spectrum antibiotic use.

In 2015, Çakmakçi [17] suggested that the engagement of surgeons in ASPs may be crucial to their success. However, Duane et al. [18] showed poor compliance of surgical services with ASP recommendations.

A retrospective study published in 2016 showed [19] that the implementation of an educational and surveillance-based ASP achieves a significant improvement in all antibiotic agent prescriptions and a reduction in antibiotics consumption. In a surgical unit performing mainly elective major abdominal surgery and emergency surgery, both a local protocol of surgical prophylaxis and a set of guidelines for management of intra-abdominal infections (IAIs) were introduced [20]. Moreover, a unit-specific control of antimicrobial agents used and surveillance of antimicrobial resistance were implemented. Comparing the pre-intervention and post-intervention periods, the mean total monthly antimicrobial use decreased significantly after the intervention. The model was based on the concept of the “surgeon champion.” The “champion” was a surgeon who on a day-to-day basis worked within the surgical unit, promoting and maintaining a culture in which both infection prevention and management were given high priority. Such a champion model has been previously applied to surgical safety implementations in general, such as surgical checklists, and plays a key role in successful quality improvement at the hospital level [21].

Identifying a local opinion leader to serve as a champion may be important because the “surgeon champion” may integrate best clinical practices and drive their colleagues into changing behaviors while maintaining a tight collaboration with antimicrobial stewardship and infection control teams. The “champion” should possess a wide knowledge of surgical microbiology, as well as considerable expertise in the antibiotic management of surgical infections. Furthermore, the “champion” should increase the awareness of surgical infections in young staff surgeons and surgical residents.

We think that the concept of the “surgeon champion” can be a crucial way to improve the infection prevention and antibiotic prescribing practices across the surgical practice pathway.

Conclusions

Surgeons must be aware that appropriate antibiotic utilization is an integral part of any stewardship program and necessary to maximize clinical cure and minimize the emergence of antimicrobial resistance.

Antimicrobial restriction is not more effective than the persuasive strategy in achieving the goal of controlling antimicrobial use in the long term [22]. Moreover, in many settings, there may be inadequate personnel for a restrictive approach, and restriction strategies fail to consider the appropriateness of use of non-restricted antibiotics, which makes up the vast majority of antibiotics used in the hospital [23]. The impact on surgeon autonomy with antimicrobial restriction may also create barriers to collaboration with members of the ASP resulting in less communication about stewardship. Therefore, the emphasis needs to be on the incorporation of a surgeon champion in the ASPs.

Surgeons with good knowledge of surgical infections involved in ASPs may audit antibiotic prescriptions, provide feedback to the prescribers, and integrate the best practice of infection prevention and management among surgeons. We think that the concept of the “surgeon champion” is a crucial way to improve infection prevention and antibiotic prescribing practices across the surgical practice pathway.

Abbreviations

AMR:

Antimicrobial resistance

ASP:

Antimicrobial stewardship program

HAIs:

Healthcare-associated infections

PAP:

Preoperative antibiotic prophylaxis

SSI:

Surgical site infection

References

  1. 1.

    Global Alliance for Infections in Surgery Working Group. A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway. Surg Infect (Larchmt). 2017;18:846-53.

  2. 2.

    Itani KMF, May AK. Surgical Infection Society: we endorse antimicrobial stewardship we stand by our international colleagues and societies in the fight for proper antimicrobial therapy. Surg Infect (Larchmt). 2017;18:843–5.

    Article  Google Scholar 

  3. 3.

    Zimlichman E, Henderson D, Tamir O, Franz C, Song P, Yamin CK, et al. Health care-associated infections: a meta-analysis of costs and financial impact on the US health care system. JAMA Intern Med. 2013;173:2039–46.

    Article  PubMed  Google Scholar 

  4. 4.

    GlobalSurg Collaborative. Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study. Lancet Infect Dis. 2018;18:516–25.

    Article  Google Scholar 

  5. 5.

    Allegranzi B, Zayed B, Bischoff P, Kubilay NZ, de Jonge S, de Vries F, et al. New WHO recommendations on intraoperative and postoperative measures for surgical site infection prevention: an evidence-based global perspective. Lancet Infect Dis. 2016;16:e288–303.

    Article  PubMed  Google Scholar 

  6. 6.

    Berríos-Torres SI, Umscheid CA, Bratzler DW, Leas B, Stone EC, Kelz RR, et al. Centers for disease control and prevention guideline for the prevention of surgical site infection, 2017. JAMA Surg. 2017;152:784–91.

    Article  PubMed  Google Scholar 

  7. 7.

    Ban KA, Minei JP, Laronga C, Harbrecht BG, Jensen EH, Fry DE, et al. American College of Surgeons and Surgical Infection Society: surgical site infection guidelines, 2016 update. J Am Coll Surg. 2017;224:59–74.

    Article  PubMed  Google Scholar 

  8. 8.

    Ban KA, Laronga C, Harbrecht BG, Jensen EH, Fry DE, Itani KMF, et al. Executive summary of the American College of Surgeons/Surgical Infection Society Surgical Site Infection Guidelines-2016 update. Surg Infect. 2017;18:379–82.

    Article  Google Scholar 

  9. 9.

    Badia JM, Casey AL, Rubio-Pérez I, Crosby C, Arroyo-García N, Del Castillo JB. A survey to identify the breach between evidence and practice in the prevention of surgical infection: time to take action. Int J Surg. 2018;54(Pt A):290–7.

    Article  PubMed  Google Scholar 

  10. 10.

    Sartelli M, Weber DG, Ruppé E, Bassetti M, Wright BJ, Ansaloni L, et al. Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA). World J Emerg Surg. 2016;11:33.

    Article  PubMed  PubMed Central  Google Scholar 

  11. 11.

    Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock: 2016. Intensive Care Med. 2017;43:304–77.

    Article  PubMed  Google Scholar 

  12. 12.

    Sartelli M, Duane TM, Catena F, Tessier JM, Coccolini F, Kao LS, et al. Antimicrobial stewardship: a call to action for surgeons. Surg Infect. 2016;17:625–31.

    Article  Google Scholar 

  13. 13.

    Liu J, Li N, Hao J, Li Y, Liu A, Wu Y, Cai M. Impact of the antibiotic stewardship program on prevention and control of surgical site infection during peri-operative clean surgery. Surg Infect. 2018;19:326–33.

    Article  Google Scholar 

  14. 14.

    Van Kasteren ME, Mannien J, Kullberg BJ, de Boer AS, Nagelkerke NJ, Ridderhof M, et al. Quality improvement of surgical prophylaxis in Dutch hospitals: evaluation of a multi-site intervention by time series analysis. J Antimicrob Chemother. 2005;56:1094–102.

    Article  PubMed  CAS  Google Scholar 

  15. 15.

    Huang Y, Gu J, Zhang M, Ren Z, Yang W, Chen Y, et al. Knowledge, attitude and practice of antibiotics: a questionnaire study among 2500 Chinese students. BMC Med Educ. 2013;13:163.

    Article  PubMed  PubMed Central  Google Scholar 

  16. 16.

    Dortch MJ, Fleming SB, Kauffmann RM, Dossett LA, Talbot TR, May AK. Infection reduction strategies including antibiotic stewardship protocols in surgical and trauma intensive care units are associated with reduced resistant gram-negative healthcare-associated infections. Surg Infect (Larchmt). 2011;12:15–25.

    Article  Google Scholar 

  17. 17.

    Çakmakçi M. Antibiotic stewardship programmes and the surgeon’s role. J Hosp Infect. 2015;89:264–6.

    Article  PubMed  Google Scholar 

  18. 18.

    Duane TM, Zuo JX, Wolfe LG, Bearman G, Edmond MB, Lee K, et al. Surgeons do not listen: evaluation of compliance with antimicrobial stewardship program recommendations. Am Surg. 2013;79:1269–72.

    PubMed  Google Scholar 

  19. 19.

    Sartelli M, Labricciosa FM, Scoccia L, Bellesi J, Mazzoccanti MR, Scaloni G, et al. Non-restrictive antimicrobial stewardship program in a general and emergency surgery unit. Surg Infect (Larchmt). 2016;17:485–90.

    Article  Google Scholar 

  20. 20.

    Sartelli M, Viale P, Catena F, Ansaloni L, Moore E, Malangoni M, et al. 2013 WSES guidelines for management of intra-abdominal infections. World J Emerg Surg. 2013;8:3.

    Article  PubMed  PubMed Central  Google Scholar 

  21. 21.

    Raval MV, Bentrem DJ, Eskandari MK, Ingraham AM, Hall BL, Randolph B, et al. The role of surgical champions in the American College of Surgeons National Surgical Quality Improvement Program--a national survey. J Surg Res. 2011;166:e15–25.

    Article  PubMed  Google Scholar 

  22. 22.

    Davey P, Brown E, Charani E, Fenelon L, Gould IM, Holmes A, et al. Interventions to improve antibiotic prescribing practices for hospital inpatients. Cochrane Database Syst Rev. 2013;4:CD003543.

    Google Scholar 

  23. 23.

    MacDougall C, Polk RE. Antimicrobial stewardship programs in health care systems. Clin Microbiol Rev. 2005;18:638–56.

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Availability of data and materials

The authors are responsible for the data described in the manuscript and assure full availability of the study material upon request to the corresponding author.

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Affiliations

  1. Department of Surgery, Macerata Hospital, Via Santa Lucia, 62100, Macerata, Italy

    Massimo Sartelli

  2. Department of General Surgery, Division of Surgery, Rambam Health Care Campus, Haifa, Israel

    Yoram Kluger

  3. General Surgery Department, “M. Bufalini” Cesena Hospital, Cesena, Italy

    Luca Ansaloni & Federico Coccolini

  4. Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy

    Gian Luca Baiocchi

  5. Department of Surgery, Trauma Service, Inkosi Albert Luthuli Central Hospital, Nelson R Mandela School of Clinical Medicine, Durban, South Africa

    Timothy C. Hardcastle

  6. Department of Surgery, Denver Health Medical Center, University of Colorado, Denver, CO, USA

    Ernest E. Moore

  7. Division of Trauma and Surgical Critical Care, Vanderbilt University Medical Center, Nashville, TN, USA

    Addison K. May

  8. Department of Surgery, VA Boston Health Care System, Boston University, Harvard Medical School, Boston, MA, USA

    Kamal M. F. Itani

  9. Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

    Donald E. Fry

  10. University of New Mexico School of Medicine, Albuquerque, NM, USA

    Donald E. Fry

  11. Department of Surgery, Academic Medical Center, Amsterdam, Netherlands

    Marja A. Boermeester

  12. Unit of Endocrine, Head, and Neck Surgery and Unit of Surgical Infections Support, Department of General Surgery, ParcTaulí, Hospital University, Sabadell, Spain

    Xavier Guirao

  13. Department of Surgery, University of Michigan, Ann Arbor, MI, USA

    Lena Napolitano

  14. Department of Surgery, Western Michigan University School of Medicine, Kalamazoo, MI, USA

    Robert G. Sawyer

  15. Department of Surgery, Anadolu Medical Center, Kocaali, Turkey

    Kemal Rasa

  16. Department of Surgery, College of Medicine and Health Sciences, UAE University, Al-Ain, United Arab Emirates

    Fikri M. Abu-Zidan

  17. Department of Surgery, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria

    Abdulrashid K. Adesunkanmi

  18. Department of General Surgery, Medical University of Plovdiv, UMHAT Eurohospital, Plovdiv, Bulgaria

    Boyko Atanasov

  19. Department of Surgery, University Hospital Centre Zagreb, Zagreb, Croatia

    Goran Augustin

  20. Trauma and Acute Care Surgery Unit, Hadassah Hebrew University Medical Center, Jerusalem, Israel

    Miklosh Bala

  21. Department of Surgery, Hospital Clínico Universitario, Santiago de Compostela, Spain

    Miguel A. Cainzos

  22. Department of Surgery and Obstetrics/Gynaecology, Regional Hospital, Limbe, Cameroon

    Alain Chichom-Mefire

  23. Emergency Surgery Unit, San Filippo Neri Hospital, Rome, Italy

    Francesco Cortese

  24. Department of Surgery, Royal Infirmary of Edinburgh, Edinburgh, UK

    Dimitris Damaskos

  25. Department of Surgery, University Clinical Center of Tuzla, Tuzla, Bosnia and Herzegovina

    Samir Delibegovic

  26. Department General Surgery, Kipshidze Central University Hospital, Tbilisi, Georgia

    Zaza Demetrashvili

  27. Department of Digestive Surgery, Cannes Hospital, Cannes, France

    Belinda De Simone

  28. Department of Surgery, John Peter Smith Health Network, Fort Worth, TX, USA

    Therese M. Duane

  29. Department of General Surgery, Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egypt

    Wagih Ghnnam

  30. Second Department of Surgery, Aretaieion University Hospital, National and Kapodistrian University of Athens, Athens, Greece

    George Gkiokas

  31. Faculdade de Ciências Médicas e da Saúde de Juiz de Fora, Department of Surgery, Hospital Universitário Terezinha de Jesus, Juiz de Fora, Brazil

    Carlos A. Gomes

  32. Department of General and Thoracic Surgery, University Hospital Giessen, Giessen, Germany

    Andreas Hecker

  33. Clinic for Surgery, University Clinical Center “Zvezdara”, Belgrade, Serbia

    Aleksandar Karamarkovic

  34. Third Department of General Surgery, Jagiellonian University Medical College, Krakow, Poland

    Jakub Kenig

  35. Department of Emergency Surgery, City Hospital, Mozyr, Belarus

    Vladimir Khokha

  36. Department of Surgery, Edendale Hospital, Pietermaritzburg, South Africa

    Victor Kong

  37. General Surgery Department, Magee Womens Hospital, UPMC, Pittsburgh, USA

    Arda Isik

  38. Abdominal Center, University Hospital Meilahti, Helsinki, Finland

    Ari Leppäniemi

  39. Surgical Disciplines, Immanuel Kant Baltic Federal University/Regional Clinical Hospital, Kaliningrad, Russian Federation

    Andrey Litvin

  40. 1st Department of Surgery, Kavala General Hospital, Kavala, Greece

    Eftychios Lostoridis

  41. Department of Surgery, II Cátedra de Clínica Quirúrgica, Universidad Nacional de Asunción, San Lorenzo, Paraguay

    Gustavo M. Machain & Helmut Segovia-Lohse

  42. Department of Surgery, Post-Graduate Institute of Medical Sciences, Rohtak, India

    Sanjay Marwah

  43. Department of Surgery, Radiology, University Hospital of the West Indies, Kingston, Jamaica

    Michael McFarlane

  44. Second Surgical Clinic, Emergency Hospital of Craiova, Craiova, Romania

    Cristian Mesina

  45. Department of Surgery, Emergency Hospital of Bucharest, Bucharest, Romania

    Ionut Negoi

  46. Department of Surgery, University of Ilorin Teaching Hospital, Ilorin, Nigeria

    Iyiade Olaoye

  47. Department of Surgery, UMC Ljubljana, Ljubljana, Slovenia

    Tadeja Pintar

  48. Department of General and Emergency Surgery, Riga East University Hospital “Gailezers”, Riga, Latvia

    Guntars Pupelis

  49. Department of General Surgery, Jesenice General Hospital, Jesenice, Slovenia

    Miran Rems

  50. Colorectal Surgery Unit, General Surgery Department, La Paz University Hospital, Madrid, Spain

    Ines Rubio-Perez

  51. General Surgery Department, Medical University, University Hospital St George, Plovdiv, Bulgaria

    Boris Sakakushev

  52. Faculty of Medicine, Department of Surgery, Thammasat University Hospital, Thammasat University, Amphoe Khlong Luang, Pathum Thani, Thailand

    Boonying Siribumrungwong

  53. Department of Surgery, North Estonia Medical Center, Tallinn, Estonia

    Peep Talving

  54. First Department of Surgery-Department of Abdominal, Thoracic Surgery and Traumatology, General University Hospital, Prague, Czech Republic

    Jan Ulrych

  55. Department of Surgery, Medical School University of Pécs, Pécs, Hungary

    András G. Vereczkei

  56. Global Alliance for Infections in Surgery, Porto, Portugal

    Francesco M. Labricciosa

  57. Department of Emergency Surgery, Maggiore Hospital, Parma, Italy

    Fausto Catena

Authors
  1. Massimo Sartelli
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  2. Yoram Kluger
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  3. Luca Ansaloni
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  4. Federico Coccolini
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  6. Timothy C. Hardcastle
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  7. Ernest E. Moore
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  9. Kamal M. F. Itani
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  11. Marja A. Boermeester
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  12. Xavier Guirao
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  13. Lena Napolitano
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  14. Robert G. Sawyer
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  15. Kemal Rasa
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  16. Fikri M. Abu-Zidan
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  17. Abdulrashid K. Adesunkanmi
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  18. Boyko Atanasov
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  19. Goran Augustin
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  20. Miklosh Bala
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  21. Miguel A. Cainzos
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  22. Alain Chichom-Mefire
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  23. Francesco Cortese
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  29. Wagih Ghnnam
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  30. George Gkiokas
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  31. Carlos A. Gomes
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  32. Andreas Hecker
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  33. Aleksandar Karamarkovic
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  34. Jakub Kenig
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  35. Vladimir Khokha
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  36. Victor Kong
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  37. Arda Isik
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  38. Ari Leppäniemi
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  39. Andrey Litvin
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  40. Eftychios Lostoridis
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  41. Gustavo M. Machain
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  42. Sanjay Marwah
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  43. Michael McFarlane
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  44. Cristian Mesina
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  45. Ionut Negoi
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  48. Guntars Pupelis
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  49. Miran Rems
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Contributions

MS wrote the first draft of the manuscript. All the authors reviewed the manuscript and approved the final draft.

Corresponding author

Correspondence to Massimo Sartelli.

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Appendices

Appendix 1

Strategies for a correct antibiotic prophylaxis [1]:

  1. 1.

    Antibiotics alone are unable to prevent surgical site infections. Strategies to prevent surgical site infections should always include attention to infection and prevention control strategies including correct and compliant hand hygiene practices

  2. 2.

    Antibiotic prophylaxis should be administered for operative procedures that have a high rate of postoperative surgical site infection, or when foreign materials are implanted.

  3. 3.

    Antibiotics given as prophylaxis should be effective against the aerobic and anaerobic pathogens most likely to contaminate the surgical site, i.e., Gram-positive skin commensals or normal flora colonizing the incised mucosae.

  4. 4.

    Antibiotic prophylaxis should be administered within 120 min prior to the incision. However, administration of the first dose of antibiotics beginning within 30–60 min before surgical incision is recommended for most antibiotics (e.g., cefazolin), to ensure adequate serum and tissue concentrations during the period of potential contamination. Obese patients require higher doses of antibiotic.

  5. 5.

    A single dose is generally sufficient. Additional antibiotic doses should be administered intraoperatively for procedures > 2–4 h (typically where duration exceeds two half-lives of the antibiotic) or with associated significant blood loss (> 1.5 L).

  6. 6.

    There is no evidence to support the use of postoperative antibiotic prophylaxis.

  7. 7.

    Each institution is encouraged to develop guidelines for the proper surgical prophylaxis.

Appendix 2

Strategies for a correct antibiotic therapy [1]:

  1. 1.

    The source of infection should always be identified and controlled as soon as possible.

  2. 2.

    Antibiotic empiric therapy should be initiated after a treatable surgical infection has been recognized, since microbiological data (culture and susceptibility results) may not be available for up to 48–72 h to guide the targeted therapy.

  3. 3.

    In critically ill patients, empiric broad-spectrum therapy to cover all likely pathogens should be initiated as soon as possible after a surgical infection has been recognized. Empiric antimicrobial therapy should be narrowed once the culture and susceptibility results are available and/or adequate clinical improvement is noted. In patients less severely ill, it may be pertinent to await culture results.

  4. 4.

    Empirical therapy should be chosen on the basis of local epidemiology, individual patient risk factors for multidrug-resistant bacteria, clinical severity, and infection source.

  5. 5.

    Specimens for microbiological evaluation from the site of infection are always recommended for patients with hospital-acquired or with community-acquired infections at risk for resistant pathogens (e.g., previous antimicrobial therapy, prior infection or colonization with multidrug-resistant pathogens) and in critically ill patients. Blood cultures should be performed before the administration of antibiotics in critically ill patients.

  6. 6.

    Antibiotics dose should be optimized to ensure that pharmacodynamic-pharmacokinetic targets are achieved

  7. 7.

    The appropriateness and need for antimicrobial treatment should be reassessed daily.

  8. 8.

    Once the source control is established, short courses of antibiotic therapy are as effective as longer courses regardless of the signs of inflammation according to the guidelines.

  9. 9.

    Failure of antibiotic therapy in patients having continued evidence of active infection may require a re-operation for a second source control intervention.

  10. 10.

    Biomarkers such as procalcitonin may be useful to guide the duration and/or cessation of antibiotic therapy in critically ill patients.

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Sartelli, M., Kluger, Y., Ansaloni, L. et al. Knowledge, awareness, and attitude towards infection prevention and management among surgeons: identifying the surgeon champion. World J Emerg Surg 13, 37 (2018). https://doi.org/10.1186/s13017-018-0198-x

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Keywords

  • Surgeon
  • Infection
  • Prevention
  • Antibiotic therapy

World Journal of Emergency Surgery

ISSN: 1749-7922